Registered Nurses Salary in South Carolina
As of May 2025, the median annual wage for registered nurses in South Carolina was $82,360 -15.6% vs national
South Carolina vs United States
| South Carolina | United States | |
|---|---|---|
| Median annual | $82,360 | $97,550 |
| Median hourly | $39.60 | $46.90 |
| Employment | 49,750 | 3,379,720 |
| Location quotient | 0.99 | 1.00 |
Data source: BLS OES state file (South Carolina) · U.S. BLS OES survey, May 2025
The numbers in context
For career planning: entry-level pay (10th percentile) is about $66,860, median pay is $82,360, and experienced pay (90th percentile) reaches $106,520.
Employment density in South Carolina is 0.99x the national average — a roughly average concentration of these roles in the local economy.
Frequently Asked Questions
What is the average registered nurses salary in South Carolina?
The median annual wage in South Carolina is $82,360 ($39.60 per hour), per BLS OES May 2025 data.
How does South Carolina compare to the national average for registered nurses?
The South Carolina median of $82,360 is 15.6% lower than the U.S. median of $97,550.
How many registered nurses work in South Carolina?
Approximately 49,750 are employed in South Carolina, per BLS OES.